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Post hoc analysis: use and dangers in perspective.

作者信息

Elliott H L

机构信息

Department of Medicine and Therapeutics, Western Infirmary, Glasgow, UK.

出版信息

J Hypertens Suppl. 1996 Sep;14(2):S21-4; discussion S24-5. doi: 10.1097/00004872-199609002-00006.

DOI:10.1097/00004872-199609002-00006
PMID:8934374
Abstract

DANGERS AND ADVANTAGES OF POST HOC ANALYSIS

Post hoc analysis is of major importance in the generation of hypotheses. However, the hypothesis is created by the analysis and has not been proved by any "experiment'. In some circumstances the conclusion derived from a post hoc analysis is entirely appropriate. For example, it was the only method used by Crick and Watson for determining the structure of DNA. In other circumstances, however, the results will be misleading. NEED FOR CAUTION WITH INTERPRETATION: The results of a post hoc analysis should be viewed with considerable scepticism and, in advance of confirmation by other appropriately designed prospective studies, should not be regarded as definitive proof.

摘要

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