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[人类咽上黏膜的形态学研究:10例尸检病例]

[A morphological study of human epipharyngeal mucosa: 10 autopsy cases].

作者信息

Nagai H

机构信息

Department of Otolaryngology, Kitasato University of Medicine, Kanagawa.

出版信息

Nihon Jibiinkoka Gakkai Kaiho. 1996 Mar;99(3):417-31. doi: 10.3950/jibiinkoka.99.417.

Abstract

The epipharynx lies between the nasal cavity and the mesopharynx, which is behind the oral cavity. It is a conduit for respired air, contributes to the equalization of pressure within the middle ear space via the eustachian tube and is closed by the soft palate during swallowing of food and fluid. It acts as a drainage channel for the mucous secreted by the nose and the glands within the epipharynx area. Various exchanges of the epipharyngeal mucosa occur because of the function of the epipharynx. In this study, distribution of the 3 types of epithelium in the epipharynx, which are ciliated, transitional and squamous epithelium, was investigated. The specimens of the mucosa with the bony wall of the epipharynx were collected from 10 autopsy cadavers at, (6 males and 4 females, aged from 37 to 83 years). Distribution of the 3 types of epithelium differed with the type, but there was no marked difference between the right and left halves of the epipharynx. Therefore, the distribution pattern was investigated by drawing superimposed geographical schemata of the epithelia, which were confirmed histologically in all 10 cases. The results obtained were as follows. On the superior-posterior wall, the squamous epithelium was invaginated into an area of the ciliated epithelium just like islands or bands in the nasal side and the epithelia of all 3 types were mixed in the mesopharyngeal side. The lateral wall was covered with a mixture of ciliated and transitional epithelia on the nasal side from the posterior lip of the eustachian tube and with a mixture of transitional and squamous epithelia on its mesopharyngeal side. The inferior wall was covered mostly with ciliated epithelium on the nasal side and with squamous epithelium on the mesopharyngeal side from Passavant's ridge. The transitional epithelium was distributed like an island between the areas of the ciliated and squamous epithelia in the lateral wall. The clearly definite schema of the 3 types of epithelium in the epipharynx, reported by Ali, has been generally accepted. However, the 3 types appeared as a mosaic or an island in the epipharyngeal wall and their distribution pattern was different in each individual.

摘要

鼻咽位于鼻腔和口咽后方的鼻咽之间。它是呼吸空气的通道,通过咽鼓管有助于中耳腔压力的平衡,在吞咽食物和液体时被软腭封闭。它作为鼻腔和鼻咽区域内腺体分泌的黏液的引流通道。由于鼻咽的功能,鼻咽黏膜会发生各种交换。在本研究中,对鼻咽部3种上皮类型(即纤毛上皮、移行上皮和鳞状上皮)的分布进行了调查。从10例尸检尸体(6例男性和4例女性,年龄37至83岁)收集带有鼻咽骨壁的黏膜标本。3种上皮类型的分布因类型而异,但鼻咽左右两半之间没有明显差异。因此,通过绘制上皮的叠加地理示意图来研究分布模式,所有10例均经组织学证实。获得的结果如下。在鼻咽顶后壁,鳞状上皮像岛屿或条带一样侵入鼻腔侧的纤毛上皮区域,而3种上皮类型在口咽侧混合存在。侧壁在咽鼓管后唇鼻腔侧覆盖有纤毛上皮和移行上皮的混合物,在口咽侧覆盖有移行上皮和鳞状上皮的混合物。下壁在鼻腔侧大部分覆盖有纤毛上皮,在口咽侧从帕萨万特嵴开始覆盖有鳞状上皮。移行上皮像岛屿一样分布在侧壁纤毛上皮和鳞状上皮区域之间。阿里报道的鼻咽部3种上皮类型的明确示意图已被普遍接受。然而,这3种类型在鼻咽壁上呈镶嵌或岛屿状出现,且其分布模式在每个个体中都有所不同。

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