Bärmig H, Krzoska C
Zentralbl Gynakol. 1976;98(13):792-4.
The report is presented about the treatment of the abortus imminens in the early pregnancy between the 6th and 16th weeks with a new tocolytical substance Th 1165a (Partusisten) on the basis of 61 patients. 40 of the patients reached full term delivery (41 new borns). All new borns except one with multiple chromosomal abnormalities were without any pathological evidence. Two pregnancies terminated into abortion. We could achieve tocolysis in each and every case consistantly by a special worked out scheme. Side effects, which are described due to other beta-adrenergic substances were minimal. Eventual cardiovascular side effects were prevented by additional administration of Isoptin. The results are good. Therefore the administration of Partusisten in the treatment of the imminent abortions in the early pregnancy between the 6th and 16th weeks is sensefull.
本文报告了基于61例患者,使用新型宫缩抑制剂Th 1165a(安保生)对孕6至16周的早期妊娠先兆流产进行治疗的情况。40例患者足月分娩(41例新生儿)。除1例有多种染色体异常的新生儿外,所有新生儿均无任何病理证据。2例妊娠以流产告终。通过一个特别制定的方案,我们在每一例中都能持续实现宫缩抑制。与其他β-肾上腺素能物质相关的副作用极小。通过额外给予异搏定预防了可能出现的心血管副作用。结果良好。因此,在孕6至16周的早期妊娠先兆流产治疗中使用安保生是有意义的。