人类Y染色体与SRY基因。

Human chromosome Y and SRY.

作者信息

Shah V C, Smart V

机构信息

Zoology Department, Gujarat University, Ahmedabad, India.

出版信息

Cell Biol Int. 1996 Jan;20(1):3-6. doi: 10.1006/cbir.1996.0002.

DOI:10.1006/cbir.1996.0002

PMID:8936401

Abstract

The precise location of the SRY gene on the human Y chromosome has been revealed through studies of sex reversal cases involving deletion, cross-linking and mutations of the SRY gene. Its DNA sequence and mechanism of action are being understood. Similarity of SRY with Sry of mice and its interaction with other genes in male sex determination are discussed.

摘要

通过对涉及SRY基因缺失、交联和突变的性反转病例的研究，已揭示了人类Y染色体上SRY基因的精确位置。其DNA序列和作用机制正在被了解。文中讨论了SRY与小鼠Sry的相似性及其在雄性性别决定中与其他基因的相互作用。