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镰状细胞病患儿伴反复脾隔离症发作时的部分脾切除术

Partial splenectomy in children with sickle cell disease and repeated episodes of splenic sequestration.

作者信息

Svarch E, Vilorio P, Nordet I, Chesney A, Batista J F, Torres L, González A, de la Torre E

机构信息

Instituto de Hematologia e Inmunologia, Ciudad de La Habana, Cuba.

出版信息

Hemoglobin. 1996 Nov;20(4):393-400. doi: 10.3109/03630269609005843.

DOI:10.3109/03630269609005843
PMID:8936465
Abstract

Twenty-five children with sickle cell disease and repeated episodes of splenic sequestration crises underwent partial splenectomy. They have been followed for 12 to 75 months (median 48 months) after surgery. During this period we have not observed any episode of splenic sequestration and the need for hospitalization and transfusions has been greatly reduced. We believe this is a useful and safe procedure for treating patients with this condition.

摘要

25名患有镰状细胞病且反复出现脾隔离危象的儿童接受了部分脾切除术。术后对他们进行了12至75个月(中位时间48个月)的随访。在此期间,我们未观察到任何脾隔离发作情况,住院需求和输血需求也大幅减少。我们认为这是治疗患有这种疾病患者的一种有效且安全的手术。

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Clinical and hematologic benefits of partial splenectomy for congenital hemolytic anemias in children.
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Ann Surg. 2003 Feb;237(2):281-8. doi: 10.1097/01.SLA.0000048453.61168.8F.