Saitoh K, Tsukamoto N, Mitsuhata H, Hirabayashi Y, Shimizu R
Department of Anesthesiology, Jichi Medical School, Tochigi, Japan.
Paediatr Anaesth. 1996;6(6):495-7. doi: 10.1046/j.1460-9592.1996.d01-15.x.
A three-year-old girl who underwent an operation for adrenal neuroblastoma was anaesthetized with sevoflurane and epidural analgesia. In the immediate recovery period she had convulsions. The convulsions were successfully treated with thiopentone and sevoflurane, there were no neurological sequelae. The convulsions were considered to be a manifestation of mepivacaine toxicity because of a high plasma mepivacaine concentration. Complications of paediatric regional analgesia and manifestations of mepivacaine toxicity under sevoflurane anaesthesia are discussed.
一名接受肾上腺神经母细胞瘤手术的三岁女孩，采用七氟醚和硬膜外镇痛进行麻醉。在术后即刻恢复期，她出现了惊厥。这些惊厥通过硫喷妥钠和七氟醚成功得到治疗，未留下神经后遗症。由于血浆中甲哌卡因浓度较高，惊厥被认为是甲哌卡因毒性的表现。本文讨论了小儿区域镇痛的并发症以及七氟醚麻醉下甲哌卡因毒性的表现。
