Eisenmajer R, Prior M, Leekam S, Wing L, Gould J, Welham M, Ong B
School of Psychology, La Trobe University, Bundoora, Victoria, Australia.
J Am Acad Child Adolesc Psychiatry. 1996 Nov;35(11):1523-31. doi: 10.1097/00004583-199611000-00022.
To determine what clinical symptoms clinicians have been using to distinguish between Asperger's disorder (AsD) and autistic disorder (AD).
Parents of children and adolescents with high-functioning AD (n = 48) and AsD (n = 69) were given a structured interview based on DSM-III-R and ICD-10 diagnostic criteria. Information regarding early and current symptom presentation and family, developmental, and verbal mental age information were collected. Logistic regression analyses were conducted to determine which variables best predicted clinician's diagnosis.
A number of clinical variables predicted diagnosis. Delayed language onset was the only variable of the family and developmental variables that predicted diagnosis. The AsD group was also significantly higher than the AD group in verbal mental age.
Clinicians appear to be diagnosing AsD and AD on the basis of published research and case study accounts. The findings question whether DSM-IV and ICD-10 criteria adequately describe the AsD individual, particularly in the communication domain.
确定临床医生一直以来用以区分阿斯伯格综合征(AsD)和自闭症谱系障碍(AD)的临床症状。
对患有高功能AD(n = 48)和AsD(n = 69)的儿童及青少年的家长进行基于《精神疾病诊断与统计手册》第三版修订版(DSM-III-R)和《国际疾病分类》第十版(ICD-10)诊断标准的结构化访谈。收集有关早期和当前症状表现以及家庭、发育和言语心理年龄的信息。进行逻辑回归分析以确定哪些变量最能预测临床医生的诊断。
一些临床变量可预测诊断。语言发育延迟是家庭和发育变量中唯一可预测诊断的变量。AsD组的言语心理年龄也显著高于AD组。
临床医生似乎是根据已发表的研究和案例报告来诊断AsD和AD的。这些发现质疑了《精神疾病诊断与统计手册》第四版(DSM-IV)和《国际疾病分类》第十版(ICD-10)标准是否充分描述了AsD个体,特别是在沟通领域。