[肺腺鳞癌的临床病理研究]

[A clinicopathological study of adenosquamous carcinoma of the lung].

作者信息

Mukaida T, Aoe M, Yamashita M, Date H, Hara K, Andoh A, Shimizu Y

机构信息

Department of Surgery II, Okayama University Medical School, Japan.

出版信息

Kyobu Geka. 1996 Nov;49(12):975-9; discussion 979-81.

PMID:8936996

Abstract

We studied, clinicopathologically, 34 cases of adenosquamous carcinoma (ASC) treated in our institution over the last 30 years. Its incidence was 2.3% of all primary lung cancers. Following findings were characteristics to this type of lung cancer, male dominant, old age, heavy smoker, comparatively large diameter, peripheral location, and normal level of tumor makers. The 5-year survival rates were 35.0% for ASC, 38.1% for squamous cell carcinoma (SCC), and 50.2% for adenocarcinoma (AC). The component of SCC was predominant or equal to that of AC in 27 (79.4%) ASC cases. The degree of cell differentiation was moderate and both SCC and AC components showed the same degree of cell differentiation in most cases. Lymph node metastasis was seen in 15 (48.4%) cases.

摘要

我们对本机构在过去30年中治疗的34例腺鳞癌（ASC）进行了临床病理研究。其发病率占所有原发性肺癌的2.3%。以下是这类肺癌的特征：男性居多、年龄较大、重度吸烟者、直径相对较大、位于周边以及肿瘤标志物水平正常。ASC的5年生存率为35.0%，鳞状细胞癌（SCC）为38.1%，腺癌（AC）为50.2%。在27例（79.4%）ASC病例中，SCC成分占主导或与AC成分相当。细胞分化程度为中等，在大多数情况下，SCC和AC成分的细胞分化程度相同。15例（48.4%）病例出现了淋巴结转移。