Obana Y, Furuta I, Ohba Y
Department of Clinical Pathology, Kinki University School of Medicine, Osaka-Sayama.
Rinsho Byori. 1996 Oct;44(10):956-61.
Regarding problems in emergency and urgent immunoserologic tests, I mainly focused on infectious diseases and CPR and discussed the correspondence of dangerous needle stick injuries, and the significance of emergency CRP measurement in various body fluids using highly sensitive determination methods. The actual conditions and correspondence of infections due to dangerous needle stick injuries (accidental pricking with used needles) such as hepatitis, syphilis, acquired immunodeficiency syndrome (AIDS), adult T-cell leukemia (ATL), herpes simplex, falciparum malaria, tuberculosis, Rocky mountain spotted fever, and human colonic adenocarcinoma are discussed. With regard to emergency CRP measurement, application of highly sensitive determination methods and the significance of CRP measurement of various body fluids (healthy adult blood, cord blood, cerebrospinal fluid, urine and puncture fluid) are described. The reference values for CRP concentrations in various body fluids were established at 15 to 3,063 ng/ml for serum (male; 26 to 3.992 ng/ml, female; 11 to 1,672 ng/ml), 9 to 73 ng/ml for cord blood, 2 to 10 ng/ml for cerebrospinal fluid and less than 2 ng/ml for urine.
关于急诊和紧急免疫血清学检测中的问题，我主要关注传染病和心肺复苏，并讨论了危险针刺伤的应对措施，以及使用高灵敏度检测方法在各种体液中进行急诊C反应蛋白（CRP）检测的意义。文中讨论了诸如肝炎、梅毒、获得性免疫缺陷综合征（艾滋病）、成人T细胞白血病（ATL）、单纯疱疹、恶性疟、结核病、落基山斑疹热和人结肠腺癌等因危险针刺伤（被用过的针头意外刺伤）导致感染的实际情况及应对措施。关于急诊CRP检测，介绍了高灵敏度检测方法的应用以及各种体液（健康成人血液、脐带血、脑脊液、尿液和穿刺液）CRP检测的意义。各种体液中CRP浓度的参考值设定为：血清15至3063纳克/毫升（男性；26至3992纳克/毫升，女性；11至1672纳克/毫升），脐带血9至73纳克/毫升，脑脊液2至10纳克/毫升，尿液低于2纳克/毫升。
