Potters A E, Schierbeek J M, Jansen W
Department of Obstetrics and Gynaecology, Deventer Hospital, The Netherlands.
Prenat Diagn. 1996 Oct;16(10):950-3. doi: 10.1002/(SICI)1097-0223(199610)16:10<950::AID-PD973>3.0.CO;2-W.
Holoprosencephaly is known as a spectrum of cranio-facial dysmorphia. Cyclopia is supposed to be the most extreme variant. An even more affected case, with agenesis of the eyes and orbits, is reported.