Theron J G, Payelle G G, Coskun O, Huet H F, Guimaraens L
Department of Neuroradiology and Intervenational Radiology, Centre Hospitalier Regional et Universitaire, Caen, France.
Radiology. 1996 Dec;201(3):627-36. doi: 10.1148/radiology.201.3.8939208.
To assess effectiveness of endovascular treatment of carotid artery stenosis by means of angioplasty with cerebral protection and stent placement.
Angioplasty was performed for carotid artery stenosis in 259 patients. Cerebral protection (triple coaxial catheter) was used in 136 cases of atherosclerotic stenosis in the internal carotid artery or in the carotid bifurcation and was not used in 123 cases. A stent was placed in 69 patients when images obtained immediately after angioplasty showed signs of dissection or insufficient arterial opening.
No procedure-related complications occurred in the 71 cases of nonatherosclerotic stenosis and in the 14 cases of proximal carotid artery and siphon atherosclerotic stenosis. Among the 38 patients who underwent angioplasty without cerebral protection, dissection occurred in two (5%) and embolic complication occurred in three (8%) during the procedure. Among 136 patients in whom cerebral protection was used, no embolic complications occurred during angioplasty, and two (1%) occurred during or after stent placement without protection. No residual flaps were found after stents were placed, and the restenosis rate decreased from 16% to 4%.
Endovascular treatment can be considered for all types of carotid artery stenosis. Cerebral protection is mandatory to eliminate embolic complication in cases of atherosclerotic stenosis in the internal carotid artery or carotid bifurcation. Stent placement has eliminated the risk of immediate dissection and reduced the risk of delayed restenosis.
评估采用血管成形术并结合脑保护及支架置入术对颈动脉狭窄进行血管内治疗的有效性。
对259例颈动脉狭窄患者实施血管成形术。136例颈内动脉或颈动脉分叉处动脉粥样硬化性狭窄患者采用了脑保护(三同轴导管),123例未采用。血管成形术后即刻图像显示有夹层迹象或动脉开口不足时,69例患者置入了支架。
71例非动脉粥样硬化性狭窄患者以及14例颈动脉近端和虹吸部动脉粥样硬化性狭窄患者未发生与手术相关的并发症。在38例未采用脑保护进行血管成形术的患者中,术中2例(5%)发生夹层,3例(8%)发生栓塞并发症。在136例采用脑保护的患者中,血管成形术期间未发生栓塞并发症,2例(1%)在未采用保护措施的支架置入期间或之后发生。支架置入后未发现残留瓣片,再狭窄率从16%降至4%。
所有类型的颈动脉狭窄均可考虑采用血管内治疗。对于颈内动脉或颈动脉分叉处动脉粥样硬化性狭窄病例,脑保护对于消除栓塞并发症是必不可少的。支架置入消除了即刻夹层的风险并降低了延迟再狭窄的风险。