Cunningham R P
Department of Biological Sciences, SUNY at Albany 12222, USA.
Curr Biol. 1996 Oct 1;6(10):1230-3. doi: 10.1016/s0960-9822(96)00703-8.
Cloning of the OGG1 gene from Saccharomyces cerevisiae has revealed that DNA glycosylases are not necessarily conserved throughout phylogeny, yet there is a DNA-repair protein superfamily with a wide substrate specificity found from bacteria to man.
从酿酒酵母中克隆OGG1基因的研究表明,DNA糖基化酶在整个系统发育过程中不一定是保守的,然而,从细菌到人类都发现了一个具有广泛底物特异性的DNA修复蛋白超家族。