Sclafani R A
Department of Biochemistry, Campus Box B121, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA.
Curr Opin Cell Biol. 1996 Dec;8(6):788-94. doi: 10.1016/s0955-0674(96)80079-2.
The cyclin dependent kinase activating kinase (CAK) has roles in both cell cycle regulation and transcription. CAK assembly is regulated either by additional protein binding or by phosphorylation. A recent comparison of this kinase from two yeast species shows that different proteins perform distinct roles and that the most studied CAK may function mainly in transcription.
