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外周髓鞘中的膜黏附:与蛋白P0的利弊关联

Membrane adhesion in peripheral myelin: good and bad wraps with protein P0.

作者信息

Kirschner D A, Inouye H, Saavedra R A

机构信息

Department of Biology, Boston College, Chestnut Hill, MA 02167, USA.

出版信息

Structure. 1996 Nov 15;4(11):1239-44. doi: 10.1016/s0969-2126(96)00132-3.

DOI:10.1016/s0969-2126(96)00132-3
PMID:8939762
Abstract

Recent molecular models and crystallographic analysis of the major protein of peripheral myelin have provided new insights into the molecular basis of membrane adhesion in myelin. These studies have proved useful in understanding the molecular basis of clinical phenotypes in certain demyelinating neuropathies.

摘要

近期关于周围神经髓鞘主要蛋白的分子模型和晶体学分析,为髓鞘中膜黏附的分子基础提供了新见解。这些研究已被证明有助于理解某些脱髓鞘性神经病临床表型的分子基础。

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Membrane adhesion in peripheral myelin: good and bad wraps with protein P0.外周髓鞘中的膜黏附:与蛋白P0的利弊关联
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Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.受激辐射损耗纳米显微镜揭示髓鞘碱性蛋白对脂质扩散的重组作用
Biophys J. 2016 Jun 7;110(11):2441-2450. doi: 10.1016/j.bpj.2016.04.047.
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Epitope-tagged P(0) glycoprotein causes Charcot-Marie-Tooth-like neuropathy in transgenic mice.表位标记的P(0)糖蛋白在转基因小鼠中引发了类夏科-马里-图斯病性神经病。
J Cell Biol. 2000 Nov 27;151(5):1035-46. doi: 10.1083/jcb.151.5.1035.
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Tetrameric assembly of full-sequence protein zero myelin glycoprotein by synchrotron x-ray scattering.利用同步加速器X射线散射技术对全序列髓鞘零糖蛋白进行四聚体组装。
Biophys J. 1999 Jan;76(1 Pt 1):423-37. doi: 10.1016/S0006-3495(99)77209-7.