Angus B J, Thanikkul K, Silamut K, White N J, Udomsangpetch R
Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Am J Trop Med Hyg. 1996 Nov;55(5):560-1. doi: 10.4269/ajtmh.1996.55.560.
Red blood cells infected by mature stages of Plasmodium ovale obtained from a 56-year-old Thai patient formed rosettes readily with uninfected erythrocytes. Ex vivo, the ring stage-infected erythrocytes matured well under the in vitro conditions used for P. falciparum culture, and the infected erythrocytes formed rosettes when the parasites became mature trophozoites. These rosettes were stable and remained intact until completion of schizogony. Plasmodium ovale rosettes were similar to those formed by P. falciparum- and P. vivax-infected erythrocytes. Rosette formation appears to be a common property of three species of human plasmodia.
从一名56岁泰国患者体内获取的、被卵形疟原虫成熟阶段感染的红细胞很容易与未感染的红细胞形成玫瑰花结。在体外，处于环状体阶段感染的红细胞在用于恶性疟原虫培养的体外条件下能很好地成熟，当寄生虫发育为成熟滋养体时，被感染的红细胞会形成玫瑰花结。这些玫瑰花结很稳定，在裂体增殖完成之前一直保持完整。卵形疟原虫玫瑰花结与恶性疟原虫和间日疟原虫感染的红细胞所形成的玫瑰花结相似。玫瑰花结形成似乎是三种人体疟原虫的共同特性。
