Myskowski P L, Ahkami R
Dermatology Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Med Clin North Am. 1996 Nov;80(6):1415-35. doi: 10.1016/s0025-7125(05)70496-x.
Cutaneous disorders occur with great frequency in patients with HIV infection and increase in number and severity as the disease progresses and immune function declines. In addition, the first findings related to HIV infection are often on the skin. Cutaneous infections with herpesviruses may be severe and atypical in their presentations; papillomaviruses and MC are common as well. Bacterial infections may be primary or secondary to other skin diseases; superficial and deep fungal infections are also prevalent. Papulosquamous disorders, including seborrheic dermatitis, psoriasis, and eczema, may be disfiguring and result in secondary complications. Neoplastic disorders, especially Kaposi's sarcoma, demand early diagnosis, to afford the patient maximal treatment options. All physicians must be aware of these cutaneous manifestations to decrease morbidity and improve quality of life in the HIV-infected individual.
皮肤疾病在HIV感染患者中极为常见，且随着疾病进展和免疫功能下降，其数量和严重程度会增加。此外，与HIV感染相关的最初表现往往出现在皮肤上。疱疹病毒引起的皮肤感染在表现上可能很严重且不典型；乳头瘤病毒和皮肤黏膜念珠菌病也很常见。细菌感染可能是原发性的，也可能继发于其他皮肤病；浅表和深部真菌感染也很普遍。丘疹鳞屑性疾病，包括脂溢性皮炎、银屑病和湿疹，可能会毁容并导致继发性并发症。肿瘤性疾病，尤其是卡波西肉瘤，需要早期诊断，以便为患者提供最大的治疗选择。所有医生都必须了解这些皮肤表现，以降低发病率并改善HIV感染个体的生活质量。
