Tinazzi M, Zanette G, Bonato C, Manganotti P, Polo A, Fiaschi A, Mauguière F
Servizio di Neurofisiopatologia, Istituto di Neurologia P. co Borgo Roma, Verona, Italy.
Muscle Nerve. 1996 Dec;19(12):1538-48. doi: 10.1002/(SICI)1097-4598(199612)19:12<1538::AID-MUS3>3.0.CO;2-B.
The tibial nerve P30 potential was studied in 6 patients with focal lesions located in the vicinity of the cervicomedullary junction. P30 potential was unaffected while cortical P39 was abnormal in the patients with a supramedullary lesion affecting the somatosensory pathway just above its decussation. Conversely, P30 was abnormal in the presence of a lesion situated caudally to the cervicomedullary junction affecting the lower limb sensory fibers just below their decussation. Median nerve P14 behaved similarly to the P30 potential in these cases. These clinical observations suggest that P30 potential, as P14 of median nerve somatosensory evoked potentials, is generated in the lower brain stem probably before the decussation of the sensory fibers; nucleus gracilis and medial lemniscus fibers in the lower brain stem are probably the anatomical structures generating P30 potential. This suggests that P30 potential may be used to study intraspinal and intracranial conduction times separately in the afferent somatosensory pathways.
对6例病灶位于颈髓交界处附近的患者进行了胫神经P30电位研究。在影响感觉传导通路交叉上方的髓上病变患者中，P30电位未受影响，而皮质P39电位异常。相反，在颈髓交界处尾侧存在病变影响下肢感觉纤维交叉下方时，P30电位异常。在这些病例中，正中神经P14的表现与P30电位相似。这些临床观察结果表明，P30电位与正中神经体感诱发电位的P14一样，可能在感觉纤维交叉之前于低位脑干产生；低位脑干中的薄束核和内侧丘系纤维可能是产生P30电位的解剖结构。这表明P30电位可用于分别研究传入体感通路中的脊髓内和颅内传导时间。
