CD44: one ligand, two functions.
作者信息
Aruffo A
出版信息
J Clin Invest. 1996 Nov 15;98(10):2191-2. doi: 10.1172/JCI119026.
Abstract
摘要
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CD44: one ligand, two functions.CD44：一种配体，两种功能。
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本文引用的文献
1
Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.透明质酸（HA）片段可诱导肺泡巨噬细胞中趋化因子基因表达。HA大小及CD44的作用。
J Clin Invest. 1996 Nov 15;98(10):2403-13. doi: 10.1172/JCI119054.
2
CD44 and hyaluronan-dependent rolling interactions of lymphocytes on tonsillar stroma.CD44与淋巴细胞在扁桃体基质上的透明质酸依赖性滚动相互作用。
J Cell Biol. 1996 Aug;134(4):1075-87. doi: 10.1083/jcb.134.4.1075.
3
Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages.透明质酸片段激活小鼠巨噬细胞中的NF-κB/I-κBα自调节环。
J Exp Med. 1996 May 1;183(5):2373-8. doi: 10.1084/jem.183.5.2373.
4
CD44 and its ligand hyaluronate mediate rolling under physiologic flow: a novel lymphocyte-endothelial cell primary adhesion pathway.CD44及其配体透明质酸在生理流动状态下介导滚动：一种新的淋巴细胞-内皮细胞初始黏附途径。
J Exp Med. 1996 Mar 1;183(3):1119-30. doi: 10.1084/jem.183.3.1119.
5
Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages.透明质酸盐激活CD44通过肿瘤坏死因子-α依赖机制诱导小鼠巨噬细胞中胰岛素样生长因子-1的表达。
J Clin Invest. 1993 Jun;91(6):2368-77. doi: 10.1172/JCI116469.
6
CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation.CD44对于最佳接触性过敏反应是必需的，但对于正常白细胞外渗并非必需。
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Biological markers in rheumatoid arthritis.类风湿关节炎中的生物标志物。
Semin Arthritis Rheum. 1994 Jun;23(6 Suppl 2):17-31. doi: 10.1016/0049-0172(94)90081-7.
8
Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis.抗CD44治疗可消除小鼠关节炎中的组织水肿和白细胞浸润。
Nat Med. 1995 Jun;1(6):558-63. doi: 10.1038/nm0695-558.
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Administration of antibodies to hyaluronanreceptor (CD44) delays the start and ameliorates the severity of collagen II arthritis.
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Hyaluronan binding function of CD44 is transiently activated on T cells during an in vivo immune response.在体内免疫反应期间，CD44的透明质酸结合功能在T细胞上被短暂激活。
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