J Neurotrauma. 1996 Nov;13(11):705-9. doi: 10.1089/neu.1996.13.705.
Mannitol is effective in reducing ICP, and we recommend its use in the management of traumatic intracranial hypertension. Serum osmolalities greater than 320 mOSsm/L and hypovolemia should be avoided. Some data suggest that bolus administration is preferable to continuous infusion.
甘露醇在降低颅内压方面有效,我们建议将其用于创伤性颅内高压的治疗。应避免血清渗透压大于320mOSsm/L和血容量不足。一些数据表明,推注给药优于持续输注。