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Ondansetron and hyperemesis gravidarum.
Lancet. 1993 Jan 16;341(8838):185. doi: 10.1016/0140-6736(93)90054-k.
2
Ondansetron in the prophylaxis of acute cisplatin-induced nausea and vomiting.昂丹司琼预防顺铂所致急性恶心和呕吐
Eur J Cancer Clin Oncol. 1989;25 Suppl 1:S41-5.
3
Clinical studies with ondansetron in the control of radiation-induced emesis.使用昂丹司琼控制放射性呕吐的临床研究。
Eur J Cancer Clin Oncol. 1989;25 Suppl 1:S29-33.
4
Pharmacological and anti-emetic properties of ondansetron.昂丹司琼的药理及止吐特性。
Eur J Cancer Clin Oncol. 1989;25 Suppl 1:S15-9.
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Ondansetron in the treatment of postoperative vomiting: a randomized, double-blind comparison with droperidol and metoclopramide.
Anesth Analg. 1992 Oct;75(4):561-5. doi: 10.1213/00000539-199210000-00017.
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Ondansetron and hyperemesis gravidarum.
Lancet. 1992 Nov 14;340(8829):1223. doi: 10.1016/0140-6736(92)92923-4.

用5-羟色胺3拮抗剂昂丹司琼（枢复宁）治疗妊娠剧吐。

Treatment of hyperemesis gravidarum with the 5-HT3 antagonist ondansetron (Zofran).

作者信息

Tincello D G, Johnstone M J

机构信息

Department of Obstetrics and Gynaecology, Fazakerley Hospital, Liverpool, UK.

出版信息

Postgrad Med J. 1996 Nov;72(853):688-9. doi: 10.1136/pgmj.72.853.688.

DOI:10.1136/pgmj.72.853.688
PMID:8944215
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2398636/
Abstract

Ondansetron is a 5-hydroxytryptamine receptor antagonist which is known to be a highly effective anti-emetic drug for chemotherapy-associated nausea and vomiting and for postoperative nausea. We report here a case where ondansetron was used in severe hyperemesis gravidarum to avoid parenteral nutrition. The drug was used intermittently in every trimester with no apparent adverse effects on mother or infant.

摘要

昂丹司琼是一种5-羟色胺受体拮抗剂，已知它是一种治疗化疗相关性恶心呕吐及术后恶心的高效止吐药。我们在此报告一例使用昂丹司琼治疗重度妊娠剧吐以避免肠外营养的病例。该药物在孕期各阶段间歇性使用，对母亲和婴儿均无明显不良影响。