用5-羟色胺3拮抗剂昂丹司琼（枢复宁）治疗妊娠剧吐。
Treatment of hyperemesis gravidarum with the 5-HT3 antagonist ondansetron (Zofran).
作者信息
Tincello D G, Johnstone M J
机构信息
Department of Obstetrics and Gynaecology, Fazakerley Hospital, Liverpool, UK.
出版信息
Postgrad Med J. 1996 Nov;72(853):688-9. doi: 10.1136/pgmj.72.853.688.
Abstract
Ondansetron is a 5-hydroxytryptamine receptor antagonist which is known to be a highly effective anti-emetic drug for chemotherapy-associated nausea and vomiting and for postoperative nausea. We report here a case where ondansetron was used in severe hyperemesis gravidarum to avoid parenteral nutrition. The drug was used intermittently in every trimester with no apparent adverse effects on mother or infant.
摘要
昂丹司琼是一种5-羟色胺受体拮抗剂，已知它是一种治疗化疗相关性恶心呕吐及术后恶心的高效止吐药。我们在此报告一例使用昂丹司琼治疗重度妊娠剧吐以避免肠外营养的病例。该药物在孕期各阶段间歇性使用，对母亲和婴儿均无明显不良影响。
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