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[脑膜隐球菌病。7例回顾性研究]

[Meningeal cryptococcosis. Retrospective study of 7 cases].

作者信息

Minh L, Nhi V A, Pham Y V, Van Y P, Van Thanh L

机构信息

Département de Neurologie, Faculté de Médecine de Ho Chi Minh Ville, Vietnam.

出版信息

Rev Neurol (Paris). 1996 Jun-Jul;152(6-7):465-8.

PMID:8944244
Abstract

In the analysis of medical records of 7 patients in one neurological service, different clinical aspects of cryptococcal meningitis such as diagnostic criteria, risk factors, clinical features, CSF features, and therapeutical features are reviewed. The finding on India ink preparation of Cryptococcus neoformans in the cerebrospinal fluid and the distinguishing clinical features of a chronic meningitis were the only diagnostic criteria in these 7 cases. Treatment with amphotericine B was the sole mean in the management of these cases. There were only two cases of complete cure, and 5 patients deceased. Intravenous associated with intrathecally injection of amphotericine B has been carried out in the two successfully treated patients.

摘要

在对某神经内科7例患者病历的分析中,回顾了隐球菌性脑膜炎的不同临床方面,如诊断标准、危险因素、临床特征、脑脊液特征和治疗特征。脑脊液中新型隐球菌墨汁染色的结果以及慢性脑膜炎的独特临床特征是这7例病例仅有的诊断标准。两性霉素B治疗是这些病例管理的唯一手段。仅2例完全治愈,5例患者死亡。两名成功治疗的患者采用了静脉联合鞘内注射两性霉素B的治疗方法。

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