高分化甲状腺癌
Well-differentiated thyroid carcinoma.
作者信息
Segal K, Raveh E, Lubin E, Abraham A, Shvero J, Feinmesser R
机构信息
Department of Otolaryngology, Beilinson Medical Center, Petah Tiqva, Israel.
出版信息
Am J Otolaryngol. 1996 Nov-Dec;17(6):401-6. doi: 10.1016/s0196-0709(96)90074-5.
PURPOSE
This study presents our experience with 728 patients treated in our department for well-differentiated thyroid carcinoma between 1954-1994.
MATERIALS AND METHODS
The retrospective evaluation of the prognostic implications of the clinical and pathological findings was performed. Age, sex, histological variants, tumor size, and locoregional and distant spread were evaluated as risk factors in relation to the prognosis.
RESULTS
During follow-up, which ranged from 1 to 31 years, 125 locoregional and/or distant metastases developed (17.2% of the patients), 87 of which occurred in the first 10 years after initial therapy. Thirty-two patients with papillary cancer and 20 with follicular cancer died of causes related to malignancy of the thyroid.
CONCLUSION
The experience gained in our department has led us to adopt an aggressive approach in the treatment of patients with well-differentiated carcinoma of the thyroid gland.
目的
本研究介绍了1954年至1994年间在我科接受治疗的728例高分化甲状腺癌患者的治疗经验。
材料与方法
对临床和病理结果的预后意义进行回顾性评估。将年龄、性别、组织学变异、肿瘤大小以及局部和远处转移作为与预后相关的危险因素进行评估。
结果
在为期1至31年的随访期间，发生了125例局部和/或远处转移（占患者的17.2%），其中87例发生在初始治疗后的前10年。32例乳头状癌患者和20例滤泡状癌患者死于与甲状腺恶性肿瘤相关的原因。
结论
我们科室积累的经验使我们在治疗高分化甲状腺癌患者时采取积极的治疗方法。
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