Farris S R, Grove A S
Department of Ophthalmology, Fitzsimons Army Medical Center, Aurora, Colorado 80045, USA.
Ophthalmic Plast Reconstr Surg. 1996 Dec;12(4):245-59. doi: 10.1097/00002341-199612000-00006.
Neurofibromatosis (NF) is an autosomal dominant abnormality that may effect multiple organ systems. Eyelids, orbits, and adjacent tissues may be involved with varying frequency and severity. Plexiform neurofibromas, causing mechanical ptosis and proptosis, optic nerve gliomas, and sphenoid wing dysplasia are some of the more common orbital and eyelid findings in NF. A series of 10 patients followed for up to 18 years is reported to describe features associated with NF, their clinical evolution, and their management.
神经纤维瘤病（NF）是一种常染色体显性异常疾病，可影响多个器官系统。眼睑、眼眶及相邻组织可能会以不同的频率和严重程度受累。丛状神经纤维瘤可导致机械性上睑下垂和眼球突出，视神经胶质瘤和蝶骨翼发育异常是神经纤维瘤病中一些较为常见的眼眶和眼睑表现。本文报告了一组随访长达18年的10例患者，以描述与神经纤维瘤病相关的特征、其临床演变及治疗方法。
