Gessman L, White M, Ghaly N, Raman S, Damm D, Macfie J, Timko C, Fields E
Deborah Heart and Lung Center, Browns Mills, New Jersey 08015, USA.
Pacing Clin Electrophysiol. 1996 Nov;19(11 Pt 2):1764-7. doi: 10.1111/j.1540-8159.1996.tb03220.x.
The AddVent pacemaker generator and model 1328C AV single-pass lead is a new pacemaker system capable of VDD or VDDR modes. The purpose of this study was to present the initial experience with AddVent in the United States and Canada. Between May 10, 1995 and May 3, 1996, 53 devices were implanted in 52 patients and followed for a mean of 217 (+/- 39) days. At the predischarge, 1-, 3-, and 6-month follow-up evaluations, atrial sensing thresholds and ventricular sensing and capture thresholds were measured in the supine, sitting, and standing positions to evaluate stability of atrial sensing with respect to body posture at rest. At the 1-month follow-up, a treadmill exercise test was performed to evaluate atrial sensing during exercise and to evaluate two new features of the AddVent called "sensor-mediated rate smoothing" and "preferential P wave sensing." Atrial sensing thresholds were not significantly different (P > 0.05) among body postures for any follow-up period or among follow-up periods for each posture. At rest, the percentage of appropriately tracked P waves observed was > 99% at each follow-up period. During treadmill exercise, the percentage of appropriately tracked P waves was > 98.7%. Appropriate preferential P wave sensing and sensor-mediated rate smoothing (VDDR mode) was observed. The AddVent pacing system provides safe and effective pacing therapy. Several features of VDDR pacing offer advantages over standard VDD pacing.
AddVent起搏器发生器和1328C型房室单极导线是一种新型起搏器系统，具备VDD或VDDR模式。本研究的目的是介绍AddVent在美国和加拿大的初步应用经验。1995年5月10日至1996年5月3日期间，52例患者植入了53台设备，平均随访217（±39）天。在出院前、1个月、3个月和6个月的随访评估中，测量仰卧位、坐位和站立位时的心房感知阈值以及心室感知和夺获阈值，以评估静息时身体姿势对心房感知稳定性的影响。在1个月随访时，进行了跑步机运动试验，以评估运动期间的心房感知，并评估AddVent的两项新特性，即“传感器介导的频率平滑”和“优先P波感知”。在任何随访期间，不同身体姿势之间或每种姿势的不同随访期间，心房感知阈值均无显著差异（P>0.05）。静息时，各随访期间观察到的P波适当跟踪百分比均>99%。在跑步机运动期间，P波适当跟踪百分比>98.7%。观察到了适当的优先P波感知和传感器介导的频率平滑（VDDR模式）。AddVent起搏系统提供安全有效的起搏治疗。VDDR起搏的几个特性比标准VDD起搏具有优势。
