Balas E A, Boren S A, Brown G D, Ewigman B G, Mitchell J A, Perkoff G T
Program in Health Services Management, University of Missouri, Columbia 65211, USA.
J Gen Intern Med. 1996 Oct;11(10):584-90. doi: 10.1007/BF02599025.
An American Medical Association survey reported that more than half of physicians are subjects of either clinical or economic profiling. This multilevel meta-analysis was designed to assess the clinical effect of peer-comparison feedback intervention (profiles) in changing practice patterns.
Systematic computerized and manual searches were combined to retrieve articles on randomized controlled clinical trials testing profiling reports. Eligible studies were randomized, controlled clinical trials that tested peer-comparison feedback intervention and measured utilization of clinical procedures. To use all available information, data were abstracted and analyzed on three levels: (1) direction of effects, (2) p value fro the statistical comparison, and (3) odds ratio (OR).
In the 12 eligible trials, 553 physicians were profiled. The test result was p < .05 for the vote-counting sign test of 12 studies (level 1) and p < .05 for the z-transformation test of 8 studies (level 2). There were 5 trials included in the OR analysis (level 3). The primary effect variable in two of the 5 trials had a nonsignificant OR. However, the overall OR calculated by the Mantel-Haenszel method was significant (1.091, confidence interval: 1.045 to 1.136).
Profiling has a statistically significant, but minimal effect on the utilization of clinical procedures. The results of this study indicate a need for controlled clinical evaluations before subjecting large numbers of physicians to utilization management interventions.
美国医学协会的一项调查显示,超过半数的医生成为临床或经济剖析的对象。这项多层次荟萃分析旨在评估同行比较反馈干预(剖析)在改变医疗行为模式方面的临床效果。
通过计算机系统检索和人工检索相结合的方式,检索关于测试剖析报告的随机对照临床试验的文章。符合条件的研究为随机对照临床试验,这些试验测试了同行比较反馈干预,并测量了临床程序的使用情况。为了利用所有可用信息,数据在三个层面进行提取和分析:(1)效应方向,(2)统计比较的p值,(3)比值比(OR)。
在12项符合条件的试验中,有553名医生接受了剖析。12项研究(第1层)的投票计数符号检验的测试结果为p <.05,8项研究(第2层)的z变换检验的测试结果为p <.05。OR分析(第3层)纳入了5项试验。5项试验中有2项试验的主要效应变量的OR无统计学意义。然而,通过Mantel-Haenszel方法计算的总体OR具有统计学意义(1.091,置信区间:1.045至1.136)。
剖析对临床程序的使用具有统计学意义,但影响极小。本研究结果表明,在让大量医生接受使用管理干预之前,需要进行对照临床评估。