Muth E R, Morrow G R, Jiang W, Stern R M, Dubeshter B
Department of Psychology, Pennsylvania State University, University Park 16802, USA.
J Auton Nerv Syst. 1996 Nov 6;61(2):201-3. doi: 10.1016/s0165-1838(96)00073-2.
The purpose of this short communication is to report our clinical findings regarding the use of the low frequency (LF, 0.02-0.15 Hz) and high frequency (HF, > 0.15 Hz) components of the spectral decomposition of heart-rate as indices of sympathetic (SNS) and parasympathetic nervous system (PNS) activity, respectively. Thirty-two females with histologically confirmed ovarian cancer, ranging in age from 46-72 years, participated in an autonomic assessment protocol consisting of a resting heart rate recording and several ANS function tests. The LF, HF and total power measures from the spectral decomposition were highly correlated with one another. In addition, the spectral components were most highly correlated with measures of PNS activity, i.e. standard deviation of heart rate at rest and the ratio of the six longest to the six shortest R-R intervals during deep breathing (E:I ratio). It is concluded, as other researchers have stated, that the use of the HF component of the HR spectrum as a measure of PNS activity is warranted, but caution must be used when interpreting the LF component.
本简短通讯的目的是报告我们关于将心率频谱分解的低频（LF，0.02 - 0.15 Hz）和高频（HF，> 0.15 Hz）成分分别作为交感神经系统（SNS）和副交感神经系统（PNS）活动指标的临床研究结果。32名经组织学确诊为卵巢癌的女性参与了一项自主神经评估方案，年龄在46 - 72岁之间，该方案包括静息心率记录和多项自主神经功能测试。频谱分解得到的LF、HF和总功率测量值彼此高度相关。此外，频谱成分与PNS活动指标相关性最高，即静息心率标准差以及深呼吸时六个最长与六个最短R - R间期的比值（E:I比值）。正如其他研究人员所指出的，得出的结论是，将心率频谱的HF成分用作PNS活动的测量指标是合理的，但在解释LF成分时必须谨慎。
