Horiuchi A, Kaneko T, Yamamura N, Nagata A, Nakamura T, Akamatsu T, Mukawa K, Kawa S, Kiyosawa K
Department of Internal Medicine, Suwa Red Cross Hospital, Shinshu University School of Medicine, Matsumoto, Japan.
Am J Gastroenterol. 1996 Dec;91(12):2607-9.
A 51-yr-old man, who presented with diabetes mellitus, abdominal pain, inguinal lymphadenopathy, and diffuse enlargement of the whole pancreas on ultrasonography, was at first thought to have pancreatic lymphoma. Chemotherapy including steroid was carried out successfully, although the definitive diagnosis of lymphoma was not made. However, on follow-up, we realized that both laboratory findings, such as hyperglobulinemia and autoantibody-positive results, and radiographic features in this case were very similar to those of a case of autoimmune pancreatitis recently reported by Yoshida et al. (Dig Dis Sci 1995;40:1561-8). When the disease recurred, therefore, treatment with steroid alone was performed with an excellent result. We report a case of autoimmune pancreatitis simulating primary pancreatic lymphoma.
一名51岁男性,因糖尿病、腹痛、腹股沟淋巴结肿大就诊,超声检查显示整个胰腺弥漫性肿大,最初被认为患有胰腺淋巴瘤。尽管未确诊为淋巴瘤,但包括类固醇在内的化疗仍成功实施。然而,在随访过程中,我们发现该病例的实验室检查结果,如高球蛋白血症和自身抗体阳性结果,以及影像学特征与吉田等人最近报道的自身免疫性胰腺炎病例非常相似(《消化系统疾病科学》1995年;40:1561 - 8)。因此,当疾病复发时,仅使用类固醇进行治疗,效果极佳。我们报告一例模拟原发性胰腺淋巴瘤的自身免疫性胰腺炎病例。