Tiplady B, Goodman M
J Mol Evol. 1977 Aug 5;9(4):343-7. doi: 10.1007/BF01796097.
The sequences of Petromyzon and Aplysia globins are compared with the postulated vertebrate and mollusc-vertebrate ancestors to see if differences exist in the rates of evolution of different types of residue positions. Between the mollusc-vertebrate ancestor and Aplysia globin there is no very striking pattern of changes except that the interior positions are relatively conserved. In the evolution of Petromyzon haemoglobin, the alpha 1 beta 2 contact area is relatively conserved. The homopolymeric binding of lamprey Hb seems to be a primitive function.
将七鳃鳗和海兔珠蛋白的序列与假定的脊椎动物和软体动物 - 脊椎动物祖先进行比较，以查看不同类型残基位置的进化速率是否存在差异。在软体动物 - 脊椎动物祖先和海兔珠蛋白之间，除了内部位置相对保守外，没有非常明显的变化模式。在七鳃鳗血红蛋白的进化过程中，α1β2接触区域相对保守。七鳃鳗血红蛋白的同聚物结合似乎是一种原始功能。
