Hume A L, Barbour M M, Lapane K L, Flint P M, Carleton R A
College of Pharmacy, University of Rhode Island, Kingston, USA.
Pharmacotherapy. 1996 Nov-Dec;16(6):1173-8.
This study compared the sociodemographic and cardiovascular correlates of oral contraceptive users and nonusers between 1981 and 1993. We also sought to determine changes in the prevalence of oral contraceptive use among older premenopausal women. Using data from six biennial cross-sectional household surveys in a population-based sample of two New England communities, 5239 women between ages 18 and 45 years were identified. Women using oral contraceptives were 5 years younger and better educated than nonusers, and users more frequently reported a per capita income above the median for the survey population than nonusers. Users were more likely to report smoking and have a lower body mass index than nonusers. Little use of oral contraceptives was detected among women ages 40-45 years despite changes in FDA recommendations about their use and increasing evidence of their noncontraceptive benefits in healthy older nonsmoking women.
本研究比较了1981年至1993年间口服避孕药使用者与非使用者的社会人口统计学特征及心血管相关因素。我们还试图确定老年绝经前妇女口服避孕药使用率的变化情况。利用来自新英格兰两个社区基于人群样本的六次两年一次的横断面家庭调查数据,确定了5239名年龄在18至45岁之间的女性。口服避孕药的女性比未使用者年轻5岁且受教育程度更高,与未使用者相比,使用者更频繁地报告人均收入高于调查人群的中位数。与未使用者相比,使用者更有可能报告吸烟且体重指数更低。尽管美国食品药品监督管理局(FDA)关于口服避孕药使用的建议有所变化,且越来越多的证据表明其对健康的老年不吸烟女性有非避孕益处,但在40至45岁的女性中很少检测到口服避孕药的使用情况。