Anvari M, Allen C J
Department of Surgery, McMaster University, St. Joseph's Hospital, Hamilton, Ontario, Canada.
Surg Laparosc Endosc. 1996 Dec;6(6):424-9.
The incidence and severity of dysphagia before and 6 months after laparoscopic Nissen fundoplication without routine division of short gastric vessels are presented. Laparoscopic Nissen fundoplication was undertaken in 195 patients over 32 months with 116 patients who had prospective follow-up longer than 6 months. Patients underwent a 24-h pH recording, esophageal manometry, and symptom score assessment before and 6 months after surgery. There was a significant (p < 0.0001) improvement in the percent of reflux in 24-h (8.61 +/- 0.74 to 0.68 +/- 0.12), lower esophageal pressure (8.53 +/- 0.51 to 23.11 +/- 1.1 mm Hg), and reflux symptom scores (40.97 +/- 1.13 to 12.11 +/- 1.1) at 6 months. A similar improvement (p < 0.0001) was also observed in the dysphagia symptom score (4.58 +/- 0.38 to 1.96 +/- 0.32), with more than half the patients reporting improvement after surgery. No correlation was observed between the change in dysphagia score and the postoperative lower esophageal pressure or esophageal motor function. These data suggest that the incidence of clinically significant dysphagia after laparoscopic Nissen fundoplication, even without division of short gastric vessels, is low. Improvement in the dysphagia score after surgery is interesting and warrants further investigation.
本文介绍了在不常规切断胃短血管的情况下,腹腔镜下尼氏胃底折叠术前后及术后6个月吞咽困难的发生率和严重程度。在32个月内,对195例患者实施了腹腔镜下尼氏胃底折叠术,其中116例患者进行了超过6个月的前瞻性随访。患者在手术前和术后6个月接受了24小时pH值记录、食管测压和症状评分评估。术后6个月,24小时内反流百分比(从8.61±0.74降至0.68±0.12)、食管下压力(从8.53±0.51升至23.11±1.1mmHg)和反流症状评分(从40.97±1.13降至12.11±1.1)均有显著改善(p<0.0001)。吞咽困难症状评分也有类似改善(p<0.0001)(从4.58±0.38降至1.96±0.32),超过半数患者术后报告症状改善。吞咽困难评分的变化与术后食管下压力或食管运动功能之间未观察到相关性。这些数据表明,即使不切断胃短血管,腹腔镜下尼氏胃底折叠术后临床上显著吞咽困难的发生率也较低。术后吞咽困难评分的改善很有趣,值得进一步研究。