通过不同大鼠肌肉中腺苷核苷酸和乳酸的死后变化重新审视尸僵顺序

Reconsideration of the sequence of rigor mortis through postmortem changes in adenosine nucleotides and lactic acid in different rat muscles.

作者信息

Kobayashi M, Takatori T, Iwadate K, Nakajima M

机构信息

Department of Forensic Medicine, Faculty of Medicine, University of Tokyo, Japan.

出版信息

Forensic Sci Int. 1996 Oct 25;82(3):243-53. doi: 10.1016/s0379-0738(96)02005-1.

DOI:10.1016/s0379-0738(96)02005-1

PMID:8948133

Abstract

We examined the changes in adenosine triphosphate (ATP), lactic acid, adenosine diphosphate (ADP) and adenosine monophosphate (AMP) in five different rat muscles after death. Rigor mortis has been thought to occur simultaneously in dead muscles and hence to start in small muscles sooner than in large muscles. In this study we found that the rate of decrease in ATP was significantly different in each muscle. The greatest drop in ATP was observed in the masseter muscle. These findings contradict the conventional theory of rigor mortis. Similarly, the rates of change in ADP and lactic acid, which are thought to be related to the consumption or production of ATP, were different in each muscle. However, the rate of change of AMP was the same in each muscle.

摘要

我们研究了五只不同大鼠的肌肉在死后三磷酸腺苷（ATP）、乳酸、二磷酸腺苷（ADP）和一磷酸腺苷（AMP）的变化。尸僵被认为在死亡肌肉中同时发生，因此小肌肉比大肌肉更早开始出现尸僵。在本研究中，我们发现每块肌肉中ATP的下降速率存在显著差异。咬肌中ATP下降幅度最大。这些发现与传统的尸僵理论相矛盾。同样，被认为与ATP消耗或产生相关的ADP和乳酸的变化速率在每块肌肉中也不同。然而，每块肌肉中AMP的变化速率是相同的。