van Susante J L, Buma P, Kirn H K, Salter R B
Department of Orthopedics, University Hospital Nijmegen, The Netherlands.
Acta Orthop Scand. 1996 Oct;67(5):450-4. doi: 10.3109/17453679608996666.
One hind limb in each of 20 New Zealand White rabbits was immobilized for 3 weeks together with daily forcible manipulation to induce heterotopic bone formation in the quadriceps muscle. The rabbits were then divided equally into a control group and a group treated with continuous passive motion (CPM). The effect of CPM on the development of heterotopic bone formation was assessed by radiographs of the femur and by histology. Treatment with CPM did not lead to increased heterotopic bone formation, as compared to the control group.
在20只新西兰白兔中，对每只兔子的一条后肢进行固定，持续3周，并每日进行强制手法操作，以诱导股四头肌中异位骨形成。然后将兔子平均分为对照组和持续被动运动（CPM）治疗组。通过股骨X线片和组织学评估CPM对异位骨形成发展的影响。与对照组相比，CPM治疗并未导致异位骨形成增加。
