Partin A W, Carter H B
Department of Urology, Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
Urol Clin North Am. 1996 Nov;23(4):531-40. doi: 10.1016/s0094-0143(05)70333-5.
Although there is controversy regarding the benefit of early detection of prostate cancer, it has been demonstrated that early detection can be best achieved through the use of a combination of digital rectal examination and prostate-specific antigen (PSA). This article outlines the clinical use of PSA for early detection of prostate cancer and focuses primarily on the value of molecular forms of PSA (free PSA, complexed PSA, and total PSA) in the diagnosis of localized prostate cancer.
尽管关于早期检测前列腺癌的益处存在争议，但已证明通过联合使用直肠指检和前列腺特异性抗原（PSA）能够最佳地实现早期检测。本文概述了PSA在早期检测前列腺癌中的临床应用，并主要聚焦于PSA的分子形式（游离PSA、复合PSA和总PSA）在局限性前列腺癌诊断中的价值。
