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[肝移植患者的胆管狭窄。诊断方法]

[Biliary stenosis in patients treated with liver transplantation. Diagnostic approach].

作者信息

Alvarado A A, Moreno-Gonzalez E, Gomez S R, Musella M, Loinaz S C, Gonzalez-Pinto A I, Garcia G I, Jimenez R C, Castellon P C, Rodriguez S

机构信息

Servicio de Cirugia General Digestiva y Trasplante de Organos Abdominales Jefe, Hospital Universitario 12 de Octubre, Madrid, España.

出版信息

Ann Ital Chir. 1995 Sep-Oct;66(5):711-8.

PMID:8948809
Abstract

Between April 1986 and August 1994, 393 orthotopic liver transplantation (OLT) have been performed at "12 de Octubre" Hospital. Among these ones we consider 274 OLT made in 223 adults and in 47 children (4 intraoperative deaths). The reconstruction of the biliary tract was performed with a choledocho-choledochostomy with T tube (CD-CD T) in 131 patients, a choledocho-choledochostomy without T tube or stent (CD-CD) in 75, a Roux-en-y-hepatico-jejunostomy (H-J) in 248, a hepatico-jejunostomy with stent (H-J St) in 13 and a choledocho-cholecisto-jejunostomy (CD-CC-J) in 3 patients. Thirthy six (13.3%) patients developed biliary complications (30 adults and 6 childrens). Fourteen (18.6%) occurred in CD-CD reconstruction and 13 (11.4%) in CD-CD T. The most common complications were leakage and stricture. Thirteen ERCP were performed in 12 patients (1 failed), all adults (CD-CD T: 3; CD-CD: 10). The main indication for ERCP was cholestasis and inability of non invasive methods ultrasound, scintigraphy and computerized tomography in determining the underlying etiology. ERCP was successful in all 12 patients: detecting strictures in 8, strictures + lithiasis in 1, stricture+lekage in 1 and leakage in 2. No complications were encountered after ERCP in our patients. ERCP is the method of choice in diagnosis of biliary complications in CD-CD biliary reconstruction.

摘要

1986年4月至1994年8月期间,“10月12日”医院共进行了393例原位肝移植(OLT)手术。其中,我们将223名成人和47名儿童进行的274例OLT手术(4例术中死亡)纳入研究。131例患者采用带T管的胆总管-胆总管吻合术(CD-CD T)进行胆道重建,75例采用无T管或支架的胆总管-胆总管吻合术(CD-CD),248例采用Roux-en-Y肝-空肠吻合术(H-J),13例采用带支架的肝-空肠吻合术(H-J St),3例采用胆总管-胆囊-空肠吻合术(CD-CC-J)。36例(13.3%)患者出现胆道并发症(30例成人和6例儿童)。14例(18.6%)发生在CD-CD重建中,13例(11.4%)发生在CD-CD T中。最常见的并发症是渗漏和狭窄。12例患者(1例失败)进行了13次内镜逆行胰胆管造影(ERCP),均为成人(CD-CD T:3例;CD-CD:10例)。ERCP的主要指征是胆汁淤积以及超声、闪烁扫描和计算机断层扫描等非侵入性方法无法确定潜在病因。12例患者的ERCP均成功:8例检测到狭窄,1例检测到狭窄+结石,1例检测到狭窄+渗漏,2例检测到渗漏。我们的患者在ERCP后未出现并发症。ERCP是诊断CD-CD胆道重建中胆道并发症的首选方法。

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