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隐睾的临床与细胞遗传学研究

Clinical and cytogenetic studies in undescended testes.

作者信息

Waaler P E

出版信息

Acta Paediatr Scand. 1976 Sep;65(5):553-8. doi: 10.1111/j.1651-2227.1976.tb04931.x.

DOI:10.1111/j.1651-2227.1976.tb04931.x
PMID:8949
Abstract

168 boys and 2.5-16.8 years with unilateral or bilateral undescended testes or anorchia were studied. Retention was severe (canalicular or intraabdominal) in 1/4 and moderate in 3/4 of the cases. In unilateral retention, the volume of the scrotal testis was usually normal throughout childhood whereas pubertal testicular growth was delayed. In unilateral anorchia, the scrotal testis showed compensatory hypertrophy. In all age groups examined, the mean volume of the undescended testes was abnormally small. Undescended testes were accompanied by abnormalities of the epididymis in 3.6% of cases, of the ductus deferens in 7.8% and of the spermatic vessels in 8.3%. In anorchia such abnormalities were found regularly. Inguinal hernia accompanied 62.8% of the undescended testes and was most frequent in severe cases. Patients aged 8.0-9.9 years with unilateral undescended testis had advanced bone age. Cytogenic investigations of 167 patients revealed one case of Klinefelter's syndrome (47, XXY). Gonadotrophin treatment was tried in 50 patients and was succesful in 12. Surgical results were satisfactory in 86.1% of the operated testes.

摘要

对168名年龄在2.5至16.8岁之间、患有单侧或双侧隐睾或无睾症的男孩进行了研究。在四分之一的病例中,睾丸滞留严重(在腹股沟管或腹腔内),四分之三的病例为中度滞留。在单侧睾丸滞留的情况下,整个儿童期阴囊内睾丸的体积通常正常,而青春期睾丸生长延迟。在单侧无睾症中,阴囊内睾丸表现为代偿性肥大。在所有检查的年龄组中,隐睾的平均体积异常小。3.6%的病例中,隐睾伴有附睾异常,7.8%伴有输精管异常,8.3%伴有精索血管异常。在无睾症中,这些异常经常出现。62.8%的隐睾伴有腹股沟疝,在严重病例中最为常见。年龄在8.0至9.9岁之间的单侧隐睾患者骨龄提前。对167名患者进行的细胞遗传学检查发现1例克兰费尔特综合征(47, XXY)。对50名患者尝试了促性腺激素治疗,12名患者治疗成功。86.1%的手术睾丸手术结果令人满意。

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Clinical and cytogenetic studies in undescended testes.隐睾的临床与细胞遗传学研究
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引用本文的文献

1
Evaluation of preoperative testicular volume in Japanese children with unilateral cryptorchidism.日本单侧隐睾症患儿术前睾丸体积的评估。
Int Urol Nephrol. 2008;40(4):977-81. doi: 10.1007/s11255-008-9385-0. Epub 2008 May 6.
2
A case-control study of the aetiology of cryptorchidism.隐睾症病因的病例对照研究。
J Epidemiol Community Health. 1983 Sep;37(3):238-44. doi: 10.1136/jech.37.3.238.