银屑病中的表皮重塑
Epidermal remodelling in psoriasis.
作者信息
Iizuka H, Ishida-Yamamoto A, Honda H
机构信息
Department of Dermatology, Asahikawa Medical College, Japan.
出版信息
Br J Dermatol. 1996 Sep;135(3):433-8.
PMID:8949439
Abstract
Psoriatic hyperproliferative epidermis is characterized by a regular elongation of rete ridges, accompanied by altered keratinization. Another notable finding is close positioning of the vasculature to the suprapapillary epidermis. These architectural/morphological changes are naturally described by a concept of epidermal remodelling based on decreased epidermal turnover time. The recently described positioning of stem cells to the tips of dermal papillae fits nicely with this concept.
摘要
银屑病的增生性表皮特征为表皮嵴规则延长，并伴有角化改变。另一个显著发现是脉管系统与乳头上方表皮的紧密定位。基于表皮更替时间缩短的表皮重塑概念自然地描述了这些结构/形态变化。最近描述的干细胞位于真皮乳头尖端的情况与这一概念非常契合。
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