Cerebrospinal fluid spaces before and after infant fronto-orbital advancement in unilateral coronal craniosynostosis.

Computed tomographic scan-based examination of the cerebrospinal fluid-filled spaces before and after fronto-orbital advancement in infants with unilateral coronal synostosis was performed. In infants who had not undergone surgery, pronounced compression of the ipsilateral frontal brain substance, frontal subarachnoid space, and frontal horn of the lateral ventricle were evident, with deviation of the interhemisphere fissure. After infant fronto-orbital advancement, frontal dead-space is obliterated early by expansion of the frontal subarachnoid space. Asymmetries interhemispheric fissure are slower to adapt and may be persistent some years later.