尿激酶型纤溶酶原激活剂在正常而非转化的人表皮角质形成细胞中存在细胞密度依赖性下调。 - Suppr

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超能文献

Cell density-dependent downregulation of urokinase-type plasminogen activator in normal but not in transformed human epidermal keratinocytes.

作者信息

Inndorf S, Bechtel M J, Reinartz J, Kramer M D

机构信息

Institut für Immunologie, Universität Heidelberg, Germany.

出版信息

Arch Dermatol Res. 1996 Nov;288(12):783-5. doi: 10.1007/BF02505298.

DOI:10.1007/BF02505298

PMID:8950461

Abstract

摘要

相似文献

Cell density-dependent downregulation of urokinase-type plasminogen activator in normal but not in transformed human epidermal keratinocytes.尿激酶型纤溶酶原激活剂在正常而非转化的人表皮角质形成细胞中存在细胞密度依赖性下调。

Arch Dermatol Res. 1996 Nov;288(12):783-5. doi: 10.1007/BF02505298.

Retinoic acid upregulates the plasminogen activator system in human epidermal keratinocytes.维甲酸上调人表皮角质形成细胞中的纤溶酶原激活物系统。

J Invest Dermatol. 2001 May;116(5):778-84. doi: 10.1046/j.1523-1747.2001.01310.x.

Protein kinase C mediates up-regulation of urokinase and its receptor in the migrating keratinocytes of wounded cultures, but urokinase is not required for movement across a substratum in vitro.蛋白激酶C介导损伤培养物中迁移角质形成细胞中尿激酶及其受体的上调，但体外跨基质移动并不需要尿激酶。

J Cell Physiol. 1996 Jun;167(3):500-11. doi: 10.1002/(SICI)1097-4652(199606)167:3<500::AID-JCP14>3.0.CO;2-7.

Differential expression of urokinase-type plasminogen activator (uPA), its receptor (uPA-R), and inhibitor type-2 (PAI-2) during differentiation of keratinocytes in an organotypic coculture system.在器官型共培养系统中角质形成细胞分化过程中尿激酶型纤溶酶原激活剂（uPA）、其受体（uPA-R）和2型抑制剂（PAI-2）的差异表达。

Exp Cell Res. 1995 Oct;220(2):415-23. doi: 10.1006/excr.1995.1333.

Urokinase expression and binding activity associated with the transforming growth factor beta1-induced migratory and invasive phenotype of mouse epidermal keratinocytes.尿激酶的表达及结合活性与转化生长因子β1诱导的小鼠表皮角质形成细胞迁移和侵袭表型相关。

J Cell Biochem. 1999 Jul 1;74(1):61-73.

Interaction of urokinase A chain with the receptor of human keratinocytes stimulates release of urokinase-like plasminogen activator.

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Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas.在含有Ras癌基因的转化角质形成细胞中阻断Smad4会导致与向未分化癌进展相关的Ras依赖性Erk信号通路过度激活。

Oncogene. 2000 Aug 24;19(36):4134-45. doi: 10.1038/sj.onc.1203764.

Sphingosylphosphorylcholine stimulates proliferation and upregulates cell surface-associated plasminogen activator activity in cultured human keratinocytes.鞘氨醇磷酸胆碱刺激培养的人角质形成细胞增殖并上调细胞表面相关纤溶酶原激活物活性。

J Invest Dermatol. 1998 Mar;110(3):253-8. doi: 10.1046/j.1523-1747.1998.00120.x.

Keratinocytes and head and neck squamous cell carcinoma cells regulate urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in fibroblasts.角质形成细胞和头颈部鳞状细胞癌细胞调节成纤维细胞中的尿激酶型纤溶酶原激活物和纤溶酶原激活物抑制剂-1。

Anticancer Res. 2013 Aug;33(8):3113-8.

Binding and activation of plasminogen at the surface of human keratinocytes.纤溶酶原在人角质形成细胞表面的结合与激活

Exp Cell Res. 1993 Sep;208(1):197-208. doi: 10.1006/excr.1993.1238.

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Fibrinolytic activity of earthworms extract (G-90) on lysis of fibrin clots originated from the venous blood of patients with malignant tumors.蚯蚓提取物（G-90）对源自恶性肿瘤患者静脉血的纤维蛋白凝块的纤溶活性。

Pathol Oncol Res. 1998;4(3):206-11. doi: 10.1007/BF02905250.

本文引用的文献

Binding and activation of plasminogen at the surface of human keratinocytes.纤溶酶原在人角质形成细胞表面的结合与激活

Exp Cell Res. 1993 Sep;208(1):197-208. doi: 10.1006/excr.1993.1238.

Stimulation of urokinase-type plasminogen activator expression by blockage of E-cadherin-dependent cell-cell adhesion.通过阻断E-钙黏蛋白依赖性细胞间黏附刺激尿激酶型纤溶酶原激活剂表达

Cancer Res. 1993 Aug 1;53(15):3618-23.

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness.钙黏蛋白在癌中的表达：在细胞连接形成及侵袭性预防中的作用

Biochim Biophys Acta. 1994 May 27;1198(1):11-26. doi: 10.1016/0304-419x(94)90003-5.

Coordinate expression of urinary-type plasminogen activator and its receptor accompanies malignant transformation of the ovarian surface epithelium.尿激酶型纤溶酶原激活剂及其受体的协同表达伴随着卵巢表面上皮的恶性转化。

Am J Obstet Gynecol. 1994 May;170(5 Pt 1):1285-96. doi: 10.1016/s0002-9378(94)70143-1.

The receptor for urokinase-type plasminogen activator of a human keratinocyte line (HaCaT).一种人角质形成细胞系（HaCaT）的尿激酶型纤溶酶原激活剂受体。

Exp Cell Res. 1994 Oct;214(2):486-98. doi: 10.1006/excr.1994.1286.

Plasminogen activation by human keratinocytes: molecular pathways and cell-biological consequences.

Biol Chem Hoppe Seyler. 1995 Mar;376(3):131-41. doi: 10.1515/bchm3.1995.376.3.131.

Urokinase plasminogen activator expression by primary and HPV 16-transformed keratinocytes.

Clin Exp Metastasis. 1995 Jul;13(4):260-8. doi: 10.1007/BF00133481.

Exp Cell Res. 1995 Oct;220(2):415-23. doi: 10.1006/excr.1995.1333.

Fibronectin and fibrin provide a provisional matrix for epidermal cell migration during wound reepithelialization.纤连蛋白和纤维蛋白为伤口再上皮化过程中表皮细胞迁移提供临时基质。

J Invest Dermatol. 1982 Nov;79(5):264-9. doi: 10.1111/1523-1747.ep12500075.

Urokinase- and tissue-type plasminogen activators in keratinocytes during wound reepithelialization in vivo.

J Invest Dermatol. 1988 Jun;90(6):790-5. doi: 10.1111/1523-1747.ep12461511.

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