A组链球菌中的水平基因转移：对发病机制和流行病学的影响。
Horizontal gene transfer among group A streptococci: implications for pathogenesis and epidemiology.
作者信息
Kehoe M A, Kapur V, Whatmore A M, Musser J M
机构信息
Dept of Microbiology, University of Newcastle, Medical School, Newcastle upon Tyne, UK.
出版信息
Trends Microbiol. 1996 Nov;4(11):436-43. doi: 10.1016/0966-842x(96)10058-5.
PMID:8950813
Abstract
Recent studies have revealed that there is considerable genetic diversity among the group A streptococci and that horizontal transfer and recombination of virulence genes have played a major role in generating this diversity. This finding has significant implications for our understanding of the epidemiology and pathogenesis of these common and highly versatile human pathogens.
摘要
最近的研究表明，A 组链球菌之间存在相当大的遗传多样性，并且毒力基因的水平转移和重组在产生这种多样性方面发挥了主要作用。这一发现对于我们理解这些常见且高度多能的人类病原体的流行病学和发病机制具有重要意义。
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