Hirano A
Department of Urology, Wakayama Medical College.
Hinyokika Kiyo. 1996 Oct;42(10):829-32.
We assessed the actuarial survival of 28 patients with localized prostate cancer who were treated with endocrine therapy in comparison with that of 19 patients who had radical prostatectomy between 1972 and 1995. There were no significant differences among the cause-specific curves and clinical disease-free survival of patients treated with endocrine therapy and radical prostatectomy but the all-cause survival curves favored the surgery group. The results of endocrine therapy alone were unsatisfactory for the patients with high grade tumors. In conclusion, the patients with localized prostate cancer at high risk of death from other complications are reasonable candidates for endocrine therapy.
我们评估了1972年至1995年间接受内分泌治疗的28例局限性前列腺癌患者与19例接受根治性前列腺切除术患者的精算生存率。接受内分泌治疗和根治性前列腺切除术患者的病因特异性曲线及临床无病生存率之间无显著差异,但全因生存率曲线显示手术组更具优势。对于高级别肿瘤患者,单纯内分泌治疗的效果并不理想。总之,有因其他并发症导致死亡高风险的局限性前列腺癌患者是内分泌治疗的合理候选者。