Mizrahi S S, Jones J W, Bentley F R
Department of Surgery, University of Louisville School of Medicine, Kentucky 40292, USA.
J Invest Surg. 1996 Sep-Oct;9(5):393-8. doi: 10.3109/08941939609021281.
The swine liver has been used for experimental transplantation and as an ex vivo support system for patients with fulminant hepatic failure. Preservation of liver function after the cold storage period can be accomplished by complying with several key steps during the procurement: Keep the procedure short, provide extensive exposure, allow only minimal dissection, irrigate the portal system through the splenic vein and thereby obtain regular blood flow through the organ up to the clamping point, and ice the liver abruptly in situ. This retrieval technique was used and evaluated in 10 pigs. The method allowed a short and successful organ procurement while preserving normal function of the liver ex vivo.
猪肝已被用于实验性移植,并作为暴发性肝衰竭患者的体外支持系统。在获取肝脏的过程中,遵循几个关键步骤可在冷藏期后保持肝功能:保持操作简短,充分暴露,仅进行最小限度的解剖,通过脾静脉冲洗门静脉系统,从而使器官直至夹闭点都有规律的血流,然后在原位迅速对肝脏进行冰敷。该获取技术在10头猪身上进行了应用和评估。该方法能在短时间内成功获取器官,同时在体外保持肝脏的正常功能。