Guest C, Griffith E, Lewis S Y, Moulding N
National Centre for Epidemiology and Population Health, Australian National University, Canberra.
Aust Fam Physician. 1996 Nov;25(11):1722-30.
The epidemiological bases of primary prevention and early detection of cancer of the uterine cervix are presented with emphasis on recent developments that are important for clinical practice. The progress of the implementation of the Australian cervical cancer screening policy is also discussed. A Medline search on cervical cancer, 1991-1996, was supplemented by material from international and local authorities, including reports on all aspects of cervical screening in Australia. National and international patterns of risk factors, predictors of progression and regression of precancerous lesions, cervical cancer incidence and mortality are summarised, with emphasis on the most recent and local research. Human papilloma virus (HPV) types are important causes of cervical intra-epithelial neoplasia (CIN) and squamous cell carcinoma. Most cervical screening is performed during medical consultations; additional financial incentives to promote correct targeting of this screening test should be explored. The Commonwealth Government is developing a national policy for the training of persons to provide cervical screening to supplement that provided by medical practitioners. The improvements in the national application of cervical screening should continue with the development of quality assurance at all stages of the screening pathway.
本文介绍了子宫颈癌一级预防和早期检测的流行病学基础,并重点阐述了对临床实践具有重要意义的最新进展。同时还讨论了澳大利亚子宫颈癌筛查政策的实施进展。通过检索1991 - 1996年关于子宫颈癌的医学文献,并补充来自国际和地方权威机构的资料,包括澳大利亚子宫颈筛查各方面的报告。总结了国家和国际层面的危险因素模式、癌前病变进展和消退的预测因素、子宫颈癌发病率和死亡率,并重点介绍了最新的本地研究。人乳头瘤病毒(HPV)类型是子宫颈上皮内瘤变(CIN)和鳞状细胞癌的重要病因。大多数子宫颈筛查是在医疗咨询期间进行的;应探索额外的经济激励措施,以促进这种筛查测试的正确靶向性。英联邦政府正在制定一项国家政策,培训人员提供子宫颈筛查,以补充医生提供的筛查服务。随着筛查途径各阶段质量保证的发展,应继续改进全国子宫颈筛查的应用。