中国（辽宁）人群中短串联重复序列系统HUMF13B和HUMvWF的分析。

Analysis of the short tandem repeat systems HUMF13B and HUMvWF in Chinese (Liaoning).

作者信息

Wang X, Sawaguchi T, Sawaguchi A

机构信息

Department of Legal Medicine, Tokyo Women's Medical College, Japan.

出版信息

Nihon Hoigaku Zasshi. 1996 Oct;50(5):357-60.

PMID:8952336

Abstract

The short tandem repeat (STR) systems HUMF13B and HUMvWF were investigated in 200 healthy Chinese individuals living in Liaoning (The northeast of China). The HUMF13B allele frequencies were 6 = 0.0025, 8 = 0.1825, 9 = 0.1750, 10 = 0.6325 and 11 = 0.0075; and the HUMvWF allele frequencies were 13 = 0.0300, 14 = 0.2475, 15 = 0.0450, 16 = 0.1750, 17 = 0.2600, 18 = 0.1525, 19 = 0.0725 and 20 = 0.0175. The distribution of genotypes corresponded to the Hardy-Weinberg equilibrium. The distinguishing probabilities (D.P) were calculated as 0.7318 and 0.9366; the polymorphism information content (PIC) were calculated as 0.4827 and 0.7822; and the heterozygosity (h) were calculated as 0.5378 and 0.8128, respectively. The HUMF13B and HUMvWF systems provide a useful genetic marker for human genetics, anthropological studies, and forensic science in the chinese population.

摘要

对居住在辽宁（中国东北部）的200名健康中国人进行了短串联重复序列（STR）系统HUMF13B和HUMvWF的研究。HUMF13B等位基因频率分别为：6 = 0.0025、8 = 0.1825、9 = 0.1750、10 = 0.6325和11 = 0.0075；HUMvWF等位基因频率分别为：13 = 0.0300、14 = 0.2475、15 = 0.0450、16 = 0.1750、17 = 0.2600、18 = 0.1525、19 = 0.0725和20 = 0.0175。基因型分布符合哈迪-温伯格平衡。鉴别概率（D.P）分别计算为0.7318和0.9366；多态信息含量（PIC）分别计算为0.4827和0.7822；杂合度（h）分别计算为0.5378和0.8128。HUMF13B和HUMvWF系统为中国人群的人类遗传学、人类学研究和法医学提供了有用的遗传标记。