Aizawa H, Morita K, Yamaguchi S, Sasaki N, Tobise K, Makita Y
Department of Internal Medicine, National Hospital Nayoro.
Rinsho Shinkeigaku. 1996 Jul;36(7):889-91.
A 72-year-old woman developed a sudden onset of bilateral ptosis, diplopia and gait disturbance. Neurological examination revealed bilateral oculomotor palsies, truncal ataxia, and transient slight weakness in the right upper extremity. She was diagnosed to have Nothnagel syndrome. T2-weighted MRI disclosed a high signal intensity lesion at the left paracentral portion of the upper midbrain in addition to the bilateral medial thalamic lesions, while brain CT showed only the thalamic lesions. Brain MRI was useful for detecting the small midbrain lesion.
一名72岁女性突然出现双侧上睑下垂、复视和步态障碍。神经系统检查发现双侧动眼神经麻痹、躯干共济失调以及右上肢短暂轻度无力。她被诊断为诺特纳格尔综合征。T2加权磁共振成像(MRI)显示,除双侧丘脑内侧病变外,中脑上部左侧中央旁部位有一个高信号强度病变,而脑部计算机断层扫描(CT)仅显示丘脑病变。脑部MRI有助于检测中脑小病变。