Ammon H V
Leber Magen Darm. 1977 Jun;7(3):140-8.
The current concepts of normal fat absorption and the entero-hepatic circulation of bile acids are being reviewed with emphasis on the steps which are clinically important. Based on an understanding of normal physiology, diseases associated with steatorrhea can be classified according to pathogenetic mechanisms. In some diseases the pathogenesis of the steatorrhea is not understood. Malabsorption of fat and bile salts can have characteristic consequences such as nutritional deficiencies, diarrhea, hyperoxaluria with nephrolithiasis, and cholelithiasis. For quantitative assessment of steatorrhea chemical analysis of fecal fat is necessary.
当前关于正常脂肪吸收及胆汁酸肠肝循环的概念正在重新审视,重点关注具有临床重要性的步骤。基于对正常生理学的理解,与脂肪泻相关的疾病可根据发病机制进行分类。在某些疾病中,脂肪泻的发病机制尚不清楚。脂肪和胆盐吸收不良会产生一些典型后果,如营养缺乏、腹泻、伴有肾结石的高草酸尿症和胆结石。为了对脂肪泻进行定量评估,粪便脂肪的化学分析是必要的。