Walther T, Falk V, Diegeler A, Autschbach R, Gummert J, Baryalei M, Mohr F W
Department of Cardiac Surgery, University of Leipzig, Germany.
J Heart Valve Dis. 1996 Nov;5 Suppl 3:S302-7.
Despite a variety of different artificial heart valves no ideal prosthesis for the small aortic root is yet available. Conventional stented valves are hemodynamically disadvantageous because of higher transvalvular pressure gradients. Stentless bioprostheses were implanted in such patients to evaluate their performance as an alternative to homografts and to conventional mechanical prostheses.
We analyzed 57 patients with small aortic roots who underwent stentless aortic valve replacement (Toronto SPV) from March 1993 to November 1995. All but two patients had aortic stenosis. The mean age at operation was 70.9 (+/-8.2) years. The annular diameter was 18-23 mm (mean 21.4 +/- 1.1 mm) in all patients. Of the 57 patients, 17 received a 23 mm and 40 patients a 25 mm prosthesis.
Using the oversizing technique, valve size was adjusted according to the sinotubular junction diameter, allowing a gain in prosthesis size of 2-4 mm to be achieved in all patients. On pre-discharge echocardiography maximum flow velocity was 2.3 +/- 0.4 m/s, maximum pressure gradient was 19.1 +/- 6.8 mmHg, and effective valve orifice area was 1.46 +/- 0.27 cm2. All patients were in NYHA class I or II at discharge. One patient was reoperated due to a folded annulus caused by too much oversizing. At six months follow up there was a significant reduction in pressure gradients and an increase in effective valve orifice areas in relation to a decrease in pre-existing left ventricular hypertrophy.
Stentless bioprostheses show excellent hemodynamics due to their comparably large internal diameter and flexibility. Controlled oversizing is a safe technique without additional complications. As larger valve sizes can be implanted, aortic root enlargement is not necessary. The superior hemodynamic profile of stentless aortic valves is especially advantageous in patients with small aortic roots.
尽管有多种不同的人工心脏瓣膜,但目前仍没有适用于小主动脉根部的理想假体。传统的带支架瓣膜由于跨瓣压力梯度较高,在血流动力学方面存在劣势。为评估无支架生物假体替代同种异体移植物和传统机械假体的性能,将其植入此类患者体内。
我们分析了1993年3月至1995年11月期间接受无支架主动脉瓣置换术(多伦多SPV)的57例小主动脉根部患者。除2例患者外,其余均为主动脉瓣狭窄。手术时的平均年龄为70.9(±8.2)岁。所有患者的瓣环直径为18 - 23毫米(平均21.4±1.1毫米)。57例患者中,17例接受了23毫米的假体,40例接受了25毫米的假体。
采用加大尺寸技术,根据窦管交界直径调整瓣膜尺寸,所有患者的假体尺寸均增加了2 - 4毫米。出院前超声心动图显示,最大流速为2.3±0.4米/秒,最大压力梯度为19.1±6.8毫米汞柱,有效瓣口面积为1.46±0.27平方厘米。所有患者出院时心功能均为纽约心脏协会(NYHA)I级或II级。1例患者因尺寸加大过多导致瓣环折叠而再次手术。随访6个月时,与术前左心室肥厚减轻相关,压力梯度显著降低,有效瓣口面积增加。
无支架生物假体因其相对较大的内径和柔韧性,显示出优异的血流动力学性能。控制性加大尺寸是一种安全的技术,无额外并发症。由于可植入更大尺寸的瓣膜,无需扩大主动脉根部。无支架主动脉瓣优越的血流动力学特征在小主动脉根部患者中尤为有利。