Mizoguchi T, Kuroda S, Terauchi H, Matsumura M, Nagata M
Nagata Eye Clinic, Japan.
Nippon Ganka Gakkai Zasshi. 1996 Nov;100(11):890-5.
Trabeculotomy combined with sinusotomy was performed in 30 eyes with advanced open angle glaucoma, whose intraocular pressure (IOP) had been controlled in their high teens with only topical medications. The mean pre- and postoperative IOP levels were 18.2 +/- 1.2 mmHg (mean +/- standard deviation) and 13.2 +/- 1.2 mmHg and the pressure reduction was 4.6 +/- 2.4 mmHg. Average pressure reduction was 28.8 +/- 9.3% and pressure reduction of 30% or more was obtained in 45% of the treated eyes. The pre- and postoperative medication scores were 4.47 +/- 1.50 and 3.07 +/- 1.17, respectively. There was statistically significant difference between the pre- and postoperative medication score. We had no cases in which the IOP reduction was greater than 9 mmHg and postoperative IOP was 9 mmHg or less. A 3-line drop in visual acuity was seen in only one eye. Twenty two of 30 eyes (73%) were controlled at 14 mmHg or less with medications at the last examination. These results show that trabeculotomy combined with sinusotomy in effective, and this procedure can be considered as an alternative choice for surgical treatment in advanced glaucoma.
对30例晚期开角型青光眼患者的30只眼进行小梁切开术联合鼻窦切开术,这些患者仅使用局部药物治疗时眼压控制在18 - 21mmHg。术前和术后眼压的平均水平分别为18.2±1.2mmHg(平均值±标准差)和13.2±1.2mmHg,眼压降低了4.6±2.4mmHg。平均眼压降低28.8±9.3%,45%的治疗眼眼压降低30%或更多。术前和术后药物评分分别为4.47±1.50和3.07±1.17。术前和术后药物评分之间存在统计学显著差异。我们没有出现眼压降低大于9mmHg且术后眼压为9mmHg或更低的病例。仅一只眼视力下降了3行。在最后一次检查时,30只眼中有22只眼(73%)通过药物治疗眼压控制在14mmHg或更低。这些结果表明小梁切开术联合鼻窦切开术是有效的,该手术可被视为晚期青光眼手术治疗的一种替代选择。