Ozawa H, Aono H, Saito I, Ikebe T
Department of Public Health and Hygiene, Oita Medical University.
Rinsho Byori. 1996 Nov;44(11):1015-26.
We discussed the risk factors for stroke and ischemic heart disease (IHD) as a main atherosclerotic disease. We showed that hypertension was the most principal risk factor for both cerebral hemorrhage and cerebral infarction, and the increase of total cholesterol (TCH) was inversely related with the incidence of cerebral hemorrhage. Many of the cerebral infarctions occurred where a large number of the cerebral hemorrhages did. We indicated that the mechanism of occurrence was different between stroke and IHD. In Japan, TCH has been recognized as a risk factor for IHD as same as western countries, but there are not many IHD. The mean of TCH was lower before one or two decade. But, it has increased in the last decade, and recently is nearing the level of American people in the thirties and forties. Death statistics of IHD became more accurate in Japan by reason for revision of the death certificate form from ICD-9 to ICD-10. The recognition of IHD death statistics will be changed. Incidence of stroke has been decreasing because of the decrease of hypertension. However, we will have to reconsider a preventive measure of IHD.
我们讨论了作为主要动脉粥样硬化疾病的中风和缺血性心脏病（IHD）的风险因素。我们发现，高血压是脑出血和脑梗死的最主要风险因素，而总胆固醇（TCH）的升高与脑出血的发生率呈负相关。许多脑梗死发生在大量脑出血发生的部位。我们指出，中风和IHD的发病机制不同。在日本，与西方国家一样，TCH已被视为IHD的一个风险因素，但IHD病例并不多。一二十年前TCH的平均值较低。但是，在过去十年中它有所上升，最近已接近美国三四十岁人群的水平。由于死亡证明表格从ICD - 9修订为ICD - 10，日本IHD的死亡统计数据变得更加准确。IHD死亡统计的认知将会改变。由于高血压发病率的下降，中风的发病率一直在降低。然而，我们将不得不重新考虑IHD的预防措施。
