Hammond J S, Yudd A, Schwartz L B, Margiotta M S, D'Amelio L F
Department of Surgery, University of Medicine and Dentistry of New Jersey, New Brunswick 08903-0019, USA.
Am Surg. 1996 Dec;62(12):1055-9.
Current diagnostic modalities for traumatic diaphragmatic hernia (TDH) have limitations. Prior models differ from human injury. This study evaluates peritoneoscintigraphy in a rabbit model of TDH simulating human blunt injury. Ten adult New Zealand rabbits (two control, eight experimental) underwent tracheostomy and left thoracotomy under anesthesia. Experimental animals received a radial phrenotomy (1.0 to 3.5 cm). Incisions were closed over thoracostomy tubes, and ventilation was discontinued. Catheters were inserted intraperitoneally, and radiotracer in saline was injected. A gamma counter was used to take sequential images. Transdiaphraghmatic isotope was seen in only two animals. Both had large injuries; in one, the catheter was directed toward the diaphragmatic defect. We conclude that peritoneoscintigraphy is insensitive in the detection of TDH. It is unlikely to be an effective technique coupled with diagnostic peritoneal lavage. Further efforts to refine diagnostic capability for TDH should be directed elsewhere, such as laparoscopy.
目前用于诊断创伤性膈疝(TDH)的方法存在局限性。先前的模型与人类损伤情况不同。本研究在模拟人类钝性损伤的TDH兔模型中评估腹膜闪烁造影术。十只成年新西兰兔(两只对照,八只实验)在麻醉下接受气管切开术和左胸廓切开术。实验动物接受了放射状膈切开术(1.0至3.5厘米)。切口在胸腔造瘘管上方关闭,停止通气。将导管经腹腔插入,并注入含放射性示踪剂的盐水。使用伽马计数器进行连续成像。仅在两只动物中观察到经膈同位素。两只动物均有大面积损伤;其中一只中,导管指向膈肌缺损处。我们得出结论,腹膜闪烁造影术在检测TDH方面不敏感。它不太可能是一种与诊断性腹腔灌洗相结合的有效技术。进一步提高TDH诊断能力的努力应转向其他方面,如腹腔镜检查。