Fairley K F, Roysmith J
Med J Aust. 1977 Jul 2;2(1):10-2. doi: 10.5694/j.1326-5377.1977.tb98990.x.
Vesicoureteric reflux is an important factor in pyelonephritic scar formation, but the radiological demonstration of reflux is often difficult. The influence rate of urine formation on radiological assessment of vesicoureteric reflux was studied in 21 patients. After an intravenous injection of 20 mg of frusemide, reflux was reduced or abolished in 19 of the 21 patients. In three patients, vesicoureteric reflux had not been demonstrated at an earlier examination under conditions of normal hydration, but cystourethrograms in the dehydrated state demonstrated reflux. Hydration is an important factor in assessing both the presence and degree of vesicoureteric reflux, and the incidence of false-negative results is reduced by preliminary fluid restriction. Decisions about whether reflux should be corrected surgically are usually based on the degree of reflux. Standardization of the rate of urine formation during micturating cystourethrography is therefore essential.
膀胱输尿管反流是肾盂肾炎瘢痕形成的一个重要因素，但反流的放射学显示往往很困难。对21例患者研究了尿液生成对膀胱输尿管反流放射学评估的影响率。静脉注射20毫克速尿后，21例患者中有19例反流减轻或消失。有3例患者在早期正常水化状态检查时未显示膀胱输尿管反流，但脱水状态下的膀胱尿道造影显示有反流。水化是评估膀胱输尿管反流的存在和程度的一个重要因素，通过预先限制液体摄入可降低假阴性结果的发生率。关于是否应通过手术纠正反流的决定通常基于反流的程度。因此，排尿性膀胱尿道造影期间尿液生成速率的标准化至关重要。
